Amlodipine is used to treat high blood pressure (hypertension) and severe pain in chest.
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain (angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces the amount of calcium that enters the smooth muscles of the blood vessels and heart. As muscle cells require calcium to contract, reducing the flow of calcium causes the muscle cells to relax and blood vessels to dilate, reducing blood pressure, force and rate of the heartbeat. It improves blood and oxygen supply to the heart muscles.
It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.Early intervention and start of metoprolol in myocardial infarction reduces infarct size and the incidence of ventricular fibrillation.